Ramiprilat increases bradykinin outflow from isolated hearts of rat
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چکیده
منابع مشابه
Physical Training Increases Ventricular Fibrillation Thresholds of Isolated Rat Hearts
11. Boineau JP, Schussler RB, Mooney CR, Miller CB, Wylds AC, Hudson R, Borremans JM, Brocleus CW: Natural and evoked atrial flutter due to circus movement in dogs. Role of abnormal atrial pathways, slow conduction, nonuniform refractory period distribution and premature beats. Am J Cardiol 45: 1167, 1980 12. Allessie MA, Bonke FIM, Schopman FJG: Circus movement in rabbit atrial muscle as a mec...
متن کاملIsolated Rat Hearts
The present investigation studied the effect of increasing severities of ischemic injury on recovery of oxidative metabolism after reperfusion in isolated rat hearts perfused retrogradely with erythrocyte-containing medium. Hearts subjected to 60 minutes of low-flow ischemia (5% of control perfusion) exhibited delayed but sustained recovery of left ventricular pressure development during reperf...
متن کاملIsolated Rat Hearts
The effect of perfusate [Ca2+] on the function of cardiac sarcoplasmic reticulum (CSR) was assessed by the oxalate-supported Ca2' uptake rate of ventricular homogenates of isolated rat hearts maintained in a modified Langendorif preparation. The total Ca2' pumping activity of the CSR was determined by using 20 FM ruthenium red or 625 j±M ryanodine to close the CSR Ca2+ release channel. The homo...
متن کاملAcute antihypertrophic actions of bradykinin in the rat heart: importance of cyclic GMP.
The antihypertrophic action of angiotensin (Ang)-converting enzyme (ACE) inhibitors in the heart is attributed in part to potentiation of bradykinin. Bradykinin prevents hypertrophy of cultured cardiomyocytes by releasing nitric oxide (NO) from endothelial cells, which increases cardiomyocyte guanosine 3'5'-cyclic monophosphate (cyclic GMP). It is unknown whether cyclic GMP is essential for the...
متن کاملThe effect of asafoetida essential oil on myocardial ischemic-reperfusion injury in isolated rat hearts
Objective: Previous studies reported that asafetida from Ferula assa-foetida Linn. species and its essential oil (AEO) have antioxidant effects. In the present study, the effect of AEO was evaluated on ischemic-reperfusion injury in isolated rat hearts. Materials and Methods: Forty-eight male Wistar rats were divided into 6 groups: 1) control group, 2) vehicle group, 3-5) AEO groups and, 6) car...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1993
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1993.tb12797.x